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COMBINATION THERAPY WITH PRAVASTITIN AND FENOFIBRATE ON EXPE | 56643

Journal of Health and Medical Research

Abstract

COMBINATION THERAPY WITH PRAVASTITIN AND FENOFIBRATE ON EXPERIMENTAL TRAUMATIC BRAIN INJURY

Ali Jan

Diabetic lower extremity ischemia (DLEI) causes approximately 90,000 leg amputations each year in the United States (Baser, Verpillat, Gabriel & Wang 2013). A review of the literature revealed that sufficient evidence exists to consider using pulsed electromagnetic field (PEMF) therapy as a non-invasive curative modality that could prevent many of these amputations. However, the staggering number of leg amputations following lengthy episodes of ischemic deterioration suggests a lack of consensus as to the efficacy of PEMF (Mulder, Tenenhaus & D’Souza, 2014). Therefore, the purpose of this study is to provide an evidentiary basis for using PEMF therapy in a primary care setting to promote microvascular angiogenesis and thereby prevent skin ulceration.

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