Henri Fero
Atypicalhemolyticuremicsyndromeis a rare form of thromboticmicroangiopathiesresulting from variousgeneticmutations of the complementfactors.
Thromboticmicroangiopathies include Thromboticthrombocytopenicpurpura, primary HUS furtherdividedintotypical HUS or Shiga-toxinrelated HUS, atypical HUS and secondaryforms of HUS. The most common clinicalfeatures of the HemolyticUremicSyndrome are: kidneyfailure, thrombocytopeniaresulting in hemorrhagicphenomena and alsointravascularhemolytic anemia. Mostcommonly HUS is a diagnosis made from excludingallotherplausiblecauses.
