Journal of Multiple Sclerosis

Abstract

Although sensory neurons play a significant role in regulating cutaneous inflammation, little was understood about how neurons contribute to host antimicrobial defence. Ray and colleagues have now shown that nociceptive fibers in the dermis, through their influence on dermal dendritic cells and production of IL-17A, play a critical role in antifungal defenses.

Keywords

Multiple sclerosis • Dermal Dendritic Cells • Neuropeptide • Chronic mucocutaneous candidiasis