Short Communication - (2021) Volume 0, Issue 0
Statement of the Problem: By empowerment of medical science, the mortality rate has been decreased significantly and population has aged. Therefore the co-existence of 2 or more chronic disease has become prevalence in this population. This condition can increase the complexity of therapeutic management for both health care professionals and patients. The use of multiple medications known as Polypharmacy is common in elderly population. For instance, one third of all deaths globally are as a result of cardiovascular disease. Lately, by increasing number and diversity of pharmacologic agents available, health care professionals have a lot of medications options, which can lead to Polypharmacy.
Methodology & Theoretical Orientation: The study aimed to assess the effectiveness and safety of a four-component polypill including aspirin, atorvastatin, hydrochlorothiazide, and either enalapril or valsartan for primary and secondary prevention of cardiovascular disease. This study was a two-group, pragmatic, clusterrandomised trial nested within the Golestan Cohort Study (GCS), a cohort study with 50 045 participants aged 40–75 years from the Golestan province in Iran.s.
Conclusion & Significance: Use of polypill was effective in preventing major cardiovascular events. Medication adherence was high and adverse event numbers were low. The polypill strategy could be considered as an additional effective component in controlling cardiovascular diseases, especially in LMICs
Biography:
Alireza Nateghi Baygi is a researcher in Digestive Disease Research Institute. His creative perspective in designing new drug developments such as new drug combinations or dosage forms for clinical trials leads to creation of PollyIran and SOVODAK. He is a CEO of knowledge based pharmaceutical company which is based on research and scientific methods and is in collaboration with research institutes.
Citation: Alireza Nateghi Baygi, Digestive Disease Research Institute, Iran; Multimorbidity and Polypharmacy; Current and future perspectives on the management of Polypharmacy by Fixed-dose Combination therapy.; Digital Health 2021: Oct 28-29, 2021; Osaka, Japan.
Published: 08-Jun-2021
Copyright: 2021 Nateghi Baygi A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
