Atherosclerosis is the major cause of morbidities and mortalities worldwide. In this study we aimed to review the mechanism of
atherosclerosis and its risk factors, focusing on new findings in
atherosclerosis markers and its risk factors. Furthermore, the role of
antioxidants and medicinal herbs in
atherosclerosis and endothelial damage has been discussed and a list of important
medicinal plants effective in the treatment and prevention of hyperlipidemia and
atherosclerosis is presented. Inflammation has a crucial role in
pathogenesis of atherosclerosis. The disease is accompanied by excessive fibrosis of the intima, fatty plaques formation, proliferation of smooth muscle cells, and migration of a group of
cells such as monocytes, T cells, and platelets which are formed in response to inflammation. The oxidation of low density lipoprotein (LDL) to Ox-LDL indicates the first step of
atherosclerosis in cardiovascular diseases.
Relevant Topics in General Science
