RNA interference (RNAi) may be an organic process during which RNA molecules inhibit organic phenomenon or translation, by neutralizing targeted mRNA molecules. Historically, RNAi was known by other names, including co-suppression, post-transcriptional gene silencing (PTGS), and quelling. The detailed study of every of those seemingly different processes elucidated that the identity of those phenomena were all actually RNAi. Andrew Fire and Craig C. Mello shared the 2006 Nobel prize in Physiology or Medicine for his or her work on RNA interference within the nematode Caenorhabditis elegans, which they published in 1998. Since the invention of RNAi and its regulatory potentials, it's become evident that RNAi has immense potential within the suppression of desired genes. RNAi is now referred to as precise, efficient, stable, and better than antisense technology for gene suppression. However, antisense RNA produced intracellularly by an expression vector could also be developed and find utility as novel therapeutic agents.