To determine the relative effect of multiple prognostic variables on overall post-recurrence survival time among cohorts of patients with recurrent ovarian cancer
undergoing cytoreductive surgery. The mean weighted median disease-free interval prior to cytoreductive surgery was 20.2 months, and the mean weighted median overall post-recurrence survival time was 30.3 months. The weighted mean proportion of patients in each cohort undergoing consummate cytoreductive surgery was 52.2%. Median survival amended with incrementing year of publication (p = 0.009); however, the only statistically paramount clinical variable independently associated with post-recurrence survival time was the proportion of patients undergoing consummate cytoreductive surgery (p = 0.019). After controlling for all other factors, each 10% increase in the proportion of patients undergoing consummate cytoreductive surgery was associated with a 3.0 month increase in median cohort survival time. Among patients undergoing operative intervention for recurrent ovarian cancer, the proportion of patients undergoing consummate cytoreductive surgery is independently associated with overall post-recurrence survival time. The international journals
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