Since Human Genome Project (HGP) revealed the heterogeneity of individuals, precision medicine that proposes the customized healthcare has become an intractable and hot research. Meanwhile, as the Precision Medicine Initiative launched, precision drug design which aims at maximizing therapeutic effects while minimizing undesired side effects for an individual patient has entered a new stage. One of the key strategies of precision drug design is target based drug design. Drug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient. In the most basic sense, drug design involves the design of molecules that are complementary in shape and charge to the biomolecular target with which they interact and therefore will bind to it. Drug design frequently but not necessarily relies on computer modeling techniques. This type of modeling is sometimes referred to as computer-aided drug design. Structural drug design is one of the fields of bioinformatics to finding new medications based on the knowledge of a biological target. This paper is the focus on the development of structure-based drug design for HHV infection that involves choosing the target proteins, visualizing the target structure, identifying the binding site, docking the ligands, and evaluating those using computational techniques. vs Vipan Kumar Sohpal, Computer aided structural based drug design for human herpes viral species. Journal Drug Designing Open Access provides the best peer-review articles in academic publishing is an academic journal devoted to the review of progress in some particular area or topic during a preceding period often through the means of its publishing review articles. Journal of Drug Design and Research is an interdisciplinary, open access, peer reviewed journal that brings about latest research in all related fields of Drug Design and Research focusing upon the successes in drug designing methodologies and new drugs that have been developed and the insights and advances from the combined use of chemical and biological research.
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