Medullary sponge kidney is a congenital ailment of the kidneys characterised with the aid of cystic dilatation of the collecting tubules in a single or each kidneys. people with medullary sponge kidney are at elevated hazard for kidney stones and urinary tract infection (UTI). patients with MSK typically pass twice as many stones in step with yr as do different stone formers with out MSK. while having a low morbidity charge, as many as 10% of sufferers with MSK have an elevated chance of morbidity associated with frequent stones and UTIs. whilst many patients file improved chronic kidney ache, the supply of the pain, whilst a UTI or blockage isn't present, is doubtful right now. Renal colic (flank and again pain) is present in 55% of sufferers. Ladies with MSK enjoy more stones, UTIs, and complications than guys. MSK changed into formerly believed not to be hereditary but there may be extra evidence coming forth that can imply otherwise.maximum cases are asymptomatic or are determined all through an research of blood inside the urine. Symptomatic sufferers usually gift as center-aged adults with renal colic, kidney stones, nephrocalcinosis and/or recurrent urinary tract infections; however, MSK also may additionally have an effect on kids very not often. in addition to the standard scientific phenotype of recurrent stone sickness, different scientific profiles have now been diagnosed, this is, an indolent, almost asymptomatic MSK, and a unprecedented form characterized by way of intractable pain.