Hairy mobile leukemia (HCL) is an indolent neoplasm of small mature B lymphoid cells comprising 2% of lymphoid leukemias[1] and it takes place greater often in men (male:female - 4:1) and suggest age at prognosis is about 52 years.[2] This entity, additionally called as leukemic reticuloendotheliosis, changed into first of all described in 1958 by way of Bouroncle et al.[3] This disorder is characterized with the aid of the presence of ordinary lymphoid cells with oval nuclei and considerable cytoplasm with "furry" projections related to peripheral blood and infiltrating the bone marrow and splenic purple pulp. Hairy mobile leukemia follows an indolent, however revolutionary path in which unmarried courses of cladribine result in excessive prices of whole responses (CRs).
This collection of sufferers pursuits at imparting an assessment of medical presentation, laboratory features, consisting of morphology, cytochemistry, electron microscopy and immunophenotypic profile of all instances diagnosed as HCL with special emphasis on the reaction and relapse fee with cladribine remedy.
