AIP can occur by itself or in association with other autoimmune diseases such as primary sclerosing cholangitis (PSC), primary biliary cirrhosis, retroperitoneal fibrosis, rheumatoid arthritis, sarcoidosis, and Sjögren's syndrome. Tests of your pancreas and other organs may include CT, MRI, endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatograph (ERCP). Blood tests. You will be tested for elevated levels of an immunoglobulin called IgG4, produced by your immune system. Treatments for autoimmune pancreatitis, such as long-term steroid use, also can cause complications. However, even with these complications, people who are treated for autoimmune pancreatitis have a normal life expectancy. There is no established association between AIP and pancreatic cancer. There are multiple conditions within the abdomen that can mimic acute pancreatitis,” Dr. Rendon said. “There could be an ulcer of the stomach or duodenum, or an obstruction of the intestines. Abdominal aortic aneurysm can also occur in that area, and liver inflammation can produce similar signs. TREATMENT. Unlike usual chronic pancreatitis, AIP dramatically responds to steroid therapy. Steroid therapy brings about improvement in clinical symptoms and accompanying radiological and serological abnormalities. In principle, the treatment modality of AIP can be classified into medical and surgical therapy.
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