Journal of Pharmaceutical Sciences and Drug Development

Calcium Phosphate

Calcium phosphate is a family of materials and minerals containing calcium ions together with inorganic phosphate anions. Some so-called calcium phosphates contain oxide and hydroxide as well. They are white solids of nutritious value. Calcium is necessary for many normal functions of the body, especially bone formation and maintenance. Calcium can also bind to other minerals (such as phosphate) and aid in their removal from the body. Calcium phosphate is used to prevent and to treat calcium deficiencies. Calcium phosphates include various salts of tribasic phosphoric acid (H3PO4). H2PO4−, HPO42− or PO43− ions can all be formed through progressive removal of H+ions from this acid. Their natural occurrence in skeletal tissues and teeth makes them of particular interest to both clinicians and biomedical scientists. The release of calcium and phosphorus ions regulates the activation of osteoblasts and osteoclasts to facilitate bone regeneration. The control of surface properties and porosity of calcium phosphate affects cell/protein adhesion and growth and regulatesbone mineral formation. tricalcium phosphate is a calcium salt of phosphoric acid. Its primary function in fortification is to increase the calcium content of foods.

Relevant Topics in Medical Sciences