Graphene, an sp2-hybridized, two-dimensional carbon materi- al is gaining much attention in the field of membrane science and engineering. Theoretical analysis have also predicted that graphene based membranes may exhibit orders of magnitude with greater permeability than the current state of the art mem- branes. However, most of these studies are based on a single layer of graphene sheet. Experimental studies also show that it is diffi- cult to fabricate leak-free porous graphene membranes with large surface area. In this work, we report a facile method to fabricate graphene-based composite ultrafiltration membrane in real down- stream application.