RATE, Clinical Presentations and Maternal Outcome of Cerebra | 46880

Journal of Neurology & Neurophysiology

ISSN - 2155-9562


RATE, Clinical Presentations and Maternal Outcome of Cerebral Venous Sinus Thrombosis in Pregnancy at Omdurman Maternity Hospital Khartoum, Sudan

A Bashir Fazari, Sheima Saeed, EB Gailii, SA Rahman, IM Izzeldin and K Elmusharaf

Introduction: Cerebral venous sinus thrombosis (CVST) is a relatively rare cerebrovascular disease. The clinical presentation is highly variable and diagnosis of CVST relies presence of thrombus by neuroimaging modality. CVST results in maternal mortality. Objective: The aim of this study is to identify rate, clinical presentations and maternal outcomes of cerebral venous sinus thrombosis at Omdurman Maternity Hospital, Khartoum, Sudan. Methodology: Its hospital based study for 42 cases diagnosed with CVST; the data are managed and analyzed using Statistical Package of Social Sciences (SPSS) version 17. Results: CVST rate 0.25=2.5/1000. Half of the patients are primiparous. Headache is the main presenting symptom 90.5%, papilledema (66.7%), convulsions (21.4 %), coma (9.5%), neurological deficits (9.5%) and abnormal behavior (7.1%). Overlapping of the symptoms is reported. CVST risk factors are oral contraceptive pills history (26.2%), Diabetes Mellitus (11.9%), Pregnancy Induced Hypertension (9.5%) and deep venous thrombosis (9.5%). 18 patients (42.9%) reported no relevant history or apparent risk factor. (71.4%) recovered with no disability, case disability rate is 16.7%, case fatality rate is 11.9% with high statistical significant in patients less than 20 years and those between 26 and 30 years (P=0.023). It was also higher with PIH (P=0.013), OCP (P=0.004) and cerebral hemorrhages (P=0.043). Conclusion: CVST reported high at OMH and most of them are primiparous. CVST can happen independently, CVST contributes in maternal mortality. Neuroimaging modalities improve CVST diagnosis.