Muataz Osman, Hugo Pinto, Kevin Seymour
A large number of different treatment protocols, materials and techniques have been suggested for the treatment of periimplantitis, yet there is no agreement between specialists in this field regarding the most effective regenerative intervention which can lead to complete resolution of infra-bony defects around implants or to arrest the progression of peri-implantitis. The aim of this review was to evaluate the available evidence in the literature about the benefit of using porous titaniu m granules (PTGs) as a reconstructive approach for treating infra-bony defects caused by peri-implantitis. The study searched PubMed, Ovid MEDLINE and EMBASE databases until January 2019. Animal and clinical human studies that had reported the use of PTGs for the regenerative treatment of peri-implantitis were included according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The initial electronic and manual search obtained 20 citations. After screening and determination of eligibility, 10 articles were included in the review. Results from animal and human studies, including two randomized controlled trials are too heterogeneous to allow meta-analysis. Results show that the use of PTGs for the treatment of peri-implant osseous defects can yield predictable results, although the evidence is scarce. According to the available materials one can suggest that using PTGs for treating peri-implant osseous defects could be a viable option among other available techniques. However, in case of recurrent peri-implantitis for the treated sites, a larger defect can be the result.
