Ali A. Asadi-Pooya
Knowledge of lateralizing and localizing value of seizure semiology and other clinical findings is necessary in the management process of patients with focal epilepsy, particularly with widespread use of surgery in the management of patients with refractory focal epilepsy. The advent of video-EEG monitoring has permitted careful analysis of semiologic features of seizures and their correlation with simultaneous EEG activities. The availability of new imaging and functional studies could be considered as a revolution in localization of the epileptogenic zone. In the current concise review, a list of well-documented lateralizing and localizing findings in focal epilepsies is prepared. This paper is designed as a practical tool for physicians, aiming to serve as a practical, problem-oriented reference.
While I include the correlated symptomatogenic zone and the possible mechanism in generating the finding in the context of a focal seizure, this paper emphasizes how to localize the epileptogenic zone according to any given specific finding. I hope that this paper leads to improved patient care.