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From the Interaction of Neurotoxic Peptides and Proteins wit | 70443

Journal of Cellular and Molecular Biology Research

Abstract

From the Interaction of Neurotoxic Peptides and Proteins with the Cys-loop Receptors to Novel Drugs

V.Tsetlin

The talk is devoted to research on neurotoxic proteins and peptides carried out at our Institute in collaboration with leading Russian and foreign laboratories. It focuses on toxins interacting with nicotinic acetylcholine receptors (nAChRs) and other Cys-loop receptors : glycine receptors (GlyR), ionotropiic γ-aminobutyric acid
and serotonin GABA-A and 5HT-3 receptors. Due to high homology, identification of functionally active.

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